What's the advantage of using a ring over taking a pill? Well, since there's no data yet on how much of the drug ends up in the bloodstream, there's no way to say if it will improve the potential for side effects. However, there is still one obvious, and extremely important, benefit. Unlike a PreP pill - which would need to be taken either daily or before sex, the vaginal ring could just be put in once a month and forgotten about. Just like the contraceptive ring it's adapted from, this makes it much less likely for a woman to forget to use her protection, and it should consequently make it far more effective. One of the earlier studies of PreP in women found the major reason it was ineffective was that women were forgetting to take their drugs.
I definitely look forward to seeing the results of the study. Delivering antivirals through a long-lasting vaginal ring is a great idea, and I'm thrilled that it's being explored.
Source: http://std.about.com/b/2012/06/25/hiv-if-you-hate-it-then-you-should-have-put-a-ring-on-it.htm
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